13,153 research outputs found

    Is your article EV-TRACKed?

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    The EV-TRACK knowledgebase is developed to cope with the need for transparency and rigour to increase reproducibility and facilitate standardization of extracellular vesicle (EV) research. The knowledgebase includes a checklist for authors and editors intended to improve the transparency of methodological aspects of EV experiments, allows queries and meta-analysis of EV experiments and keeps track of the current state of the art. Widespread implementation by the EV research community is key to its success

    Trade and Capital Flows: A Financial Frictions Perspective

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    The classical Heckscher-Ohlin-Mundell paradigm states that trade and capital mobility are substitutes, in the sense that trade integration reduces the incentives for capital to flow to capital-scarce countries. In this paper we show that in a world with heterogeneous financial development, the classic conclusion does not hold. In particular, in less financially developed economies (South), trade and capital mobility are complements. Within a dynamic framework, the complementarity carries over to (financial) capital flows. This interaction implies that deepening trade integration in South raises net capital inflows (or reduces net capital outflows). It also implies that, at the global level, protectionism may backfire if the goal is to rebalance capital flows, when these are already heading from South to North. Our perspective also has implications for the effects of trade integration on factor prices. In contrast to the Heckscher-Ohlin model, trade liberalization always decreases the wage-rental in South: an anti-Stolper-Samuelson result.

    Counting matroids in minor-closed classes

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    A flat cover is a collection of flats identifying the non-bases of a matroid. We introduce the notion of cover complexity, the minimal size of such a flat cover, as a measure for the complexity of a matroid, and present bounds on the number of matroids on nn elements whose cover complexity is bounded. We apply cover complexity to show that the class of matroids without an NN-minor is asymptotically small in case NN is one of the sparse paving matroids U2,kU_{2,k}, U3,6U_{3,6}, P6P_6, Q6Q_6, or R6R_6, thus confirming a few special cases of a conjecture due to Mayhew, Newman, Welsh, and Whittle. On the other hand, we show a lower bound on the number of matroids without M(K4)M(K_4)-minor which asymptoticaly matches the best known lower bound on the number of all matroids, due to Knuth.Comment: 13 pages, 3 figure

    Investigating SRAM PUFs in large CPUs and GPUs

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    Physically unclonable functions (PUFs) provide data that can be used for cryptographic purposes: on the one hand randomness for the initialization of random-number generators; on the other hand individual fingerprints for unique identification of specific hardware components. However, today's off-the-shelf personal computers advertise randomness and individual fingerprints only in the form of additional or dedicated hardware. This paper introduces a new set of tools to investigate whether intrinsic PUFs can be found in PC components that are not advertised as containing PUFs. In particular, this paper investigates AMD64 CPU registers as potential PUF sources in the operating-system kernel, the bootloader, and the system BIOS; investigates the CPU cache in the early boot stages; and investigates shared memory on Nvidia GPUs. This investigation found non-random non-fingerprinting behavior in several components but revealed usable PUFs in Nvidia GPUs.Comment: 25 pages, 6 figures. Code in appendi

    Forelimb muscle and joint actions in Archosauria: insights from Crocodylus johnstoni (Pseudosuchia) and Mussaurus patagonicus (Sauropodomorpha)

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    Many of the major locomotor transitions during the evolution of Archosauria, the lineage including crocodiles and birds as well as extinct Dinosauria, were shifts from quadrupedalism to bipedalism (and vice versa). Those occurred within a continuum between more sprawling and erect modes of locomotion and involved drastic changes of limb anatomy and function in several lineages, including sauropodomorph dinosaurs. We present biomechanical computer models of two locomotor extremes within Archosauria in an analysis of joint ranges of motion and the moment arms of the major forelimb muscles in order to quantify biomechanical differences between more sprawling, pseudosuchian (represented the crocodile Crocodylus johnstoni) and more erect, dinosaurian (represented by the sauropodomorph Mussaurus patagonicus) modes of forelimb function. We compare these two locomotor extremes in terms of the reconstructed musculoskeletal anatomy, ranges of motion of the forelimb joints and the moment arm patterns of muscles across those ranges of joint motion. We reconstructed the three-dimensional paths of 30 muscles acting around the shoulder, elbow and wrist joints. We explicitly evaluate how forelimb joint mobility and muscle actions may have changed with postural and anatomical alterations from basal archosaurs to early sauropodomorphs. We thus evaluate in which ways forelimb posture was correlated with muscle leverage, and how such differences fit into a broader evolutionary context (i.e. transition from sprawling quadrupedalism to erect bipedalism and then shifting to graviportal quadrupedalism). Our analysis reveals major differences of muscle actions between the more sprawling and erect models at the shoulder joint. These differences are related not only to the articular surfaces but also to the orientation of the scapula, in which extension/flexion movements in Crocodylus (e.g. protraction of the humerus) correspond to elevation/depression in Mussaurus. Muscle action is highly influenced by limb posture, more so than morphology. Habitual quadrupedalism in Mussaurus is not supported by our analysis of joint range of motion, which indicates that glenohumeral protraction was severely restricted. Additionally, some active pronation of the manus may have been possible in Mussaurus, allowing semi-pronation by a rearranging of the whole antebrachium (not the radius against the ulna, as previously thought) via long-axis rotation at the elbow joint. However, the muscles acting around this joint to actively pronate it may have been too weak to drive or maintain such orientations as opposed to a neutral position in between pronation and supination. Regardless, the origin of quadrupedalism in Sauropoda is not only linked to manus pronation but also to multiple shifts of forelimb morphology, allowing greater flexion movements of the glenohumeral joint and a more columnar forelimb posture

    On the number of matroids

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    We consider the problem of determining mnm_n, the number of matroids on nn elements. The best known lower bound on mnm_n is due to Knuth (1974) who showed that loglogmn\log \log m_n is at least n3/2logn1n-3/2\log n-1. On the other hand, Piff (1973) showed that loglogmnnlogn+loglogn+O(1)\log\log m_n\leq n-\log n+\log\log n +O(1), and it has been conjectured since that the right answer is perhaps closer to Knuth's bound. We show that this is indeed the case, and prove an upper bound on loglogmn\log\log m_n that is within an additive 1+o(1)1+o(1) term of Knuth's lower bound. Our proof is based on using some structural properties of non-bases in a matroid together with some properties of independent sets in the Johnson graph to give a compressed representation of matroids.Comment: Final version, 17 page

    An entropy argument for counting matroids

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    We show how a direct application of Shearers' Lemma gives an almost optimum bound on the number of matroids on nn elements.Comment: Short note, 4 page

    Optically activated ZnO/Sio2/Si cantilever beams

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    The photomechanical effect induced by periodically varying sub-bandgap illumination in thin ZnO films deposited on oxidized Si has been demonstrated for the first time. The efficiency of this effect is at least one order of magnitude higher as compared to the photothermal activation of Si. Thus it can be considered as a powerful optical drive for resonant sensors. A phenomenological model of the mechanisms involved in the process is proposed. The optomechanical effect can also be used as a complementary method in determination of the surface state parameters of ZnO films
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